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PE5–PPE4–EspG(3) heterotrimer structure from mycobacterial ESX-3 secretion system gives insight into cognate substrate recognition by ESX systems

Mycobacterium tuberculosis has evolved numerous type VII secretion (ESX) systems to secrete multiple factors important for both growth and virulence across their cell envelope. ESX-1, ESX-3, and ESX-5 systems have been shown to each secrete a distinct set of substrates, including PE and PPE families...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Williamson, Zachary A., Chaton, Catherine T., Ciocca, William A., Korotkova, Natalia, Korotkov, Konstantin V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476729/
https://ncbi.nlm.nih.gov/pubmed/32675282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012698
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