Structural variability of EspG chaperones from mycobacterial ESX-1, ESX-3 and ESX-5 type VII secretion systems

Type VII secretion systems (ESX) are responsible for transport of multiple proteins in mycobacteria. How different ESX systems achieve specific secretion of cognate substrates remains elusive. In the ESX systems, the cytoplasmic chaperone EspG forms complexes with heterodimeric PE-PPE substrates tha...

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Foilsithe in:J Mol Biol
Main Authors: Tuukkanen, Anne T., Freire, Diana, Chan, Sum, Arbing, Mark A., Reed, Robert W., Evans, Timothy J., Zenkeviciutė, Grasilda, Kim, Jennifer, Kahng, Sara, Sawaya, Michael R., Chaton, Catherine T., Wilmanns, Matthias, Eisenberg, David, Parret, Annabel H. A., Korotkov, Konstantin V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6331215/
https://ncbi.nlm.nih.gov/pubmed/30419243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.11.003
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