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Structures of EccB(1) and EccD(1) from the core complex of the mycobacterial ESX-1 type VII secretion system

BACKGROUND: The ESX-1 type VII secretion system is an important determinant of virulence in pathogenic mycobacteria, including Mycobacterium tuberculosis. This complicated molecular machine secretes folded proteins through the mycobacterial cell envelope to subvert the host immune response. Despite...

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Detalhes bibliográficos
Publicado no:BMC Struct Biol
Main Authors: Wagner, Jonathan M., Chan, Sum, Evans, Timothy J., Kahng, Sara, Kim, Jennifer, Arbing, Mark A., Eisenberg, David, Korotkov, Konstantin V.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4769845/
https://ncbi.nlm.nih.gov/pubmed/26922638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12900-016-0056-6
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