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Structure of a PE–PPE–EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion

Nearly 10% of the coding capacity of the Mycobacterium tuberculosis genome is devoted to two highly expanded and enigmatic protein families called PE and PPE, some of which are important virulence/immunogenicity factors and are secreted during infection via a unique alternative secretory system term...

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Detalhes bibliográficos
Main Authors: Ekiert, Damian C., Cox, Jeffery S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205667/
https://ncbi.nlm.nih.gov/pubmed/25275011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409345111
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