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Pendrin stimulates a chloride absorption pathway to increase CFTR‐mediated chloride secretion from Cystic Fibrosis airway epithelia

Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secretion may be curative for CF, so different components of the i...

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Detalhes bibliográficos
Publicado no:FASEB Bioadv
Main Authors: Bajko, Jeffrey, Duguid, Mei, Altmann, Steve, Hurlbut, Gregory D., Kaczmarek, J. Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475303/
https://ncbi.nlm.nih.gov/pubmed/32923987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00012
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