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Pendrin stimulates a chloride absorption pathway to increase CFTR‐mediated chloride secretion from Cystic Fibrosis airway epithelia

Cystic Fibrosis (CF), an inherited multi‐system disease, is caused by mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) that disrupt its ability to secrete anions from epithelia. Recovery of functional anion secretion may be curative for CF, so different components of the i...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:FASEB Bioadv
Prif Awduron: Bajko, Jeffrey, Duguid, Mei, Altmann, Steve, Hurlbut, Gregory D., Kaczmarek, J. Stefan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475303/
https://ncbi.nlm.nih.gov/pubmed/32923987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fba.2020-00012
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