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Novel Role for Pendrin in Orchestrating Bicarbonate Secretion in Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-expressing Airway Serous Cells

In most HCO(3)(−)-secreting epithelial tissues, SLC26 Cl(−)/HCO(3)(−) transporters work in concert with the cystic fibrosis transmembrane conductance regulator (CFTR) to regulate the magnitude and composition of the secreted fluid, a process that is vital for normal tissue function. By contrast, CFT...

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Detalhes bibliográficos
Main Authors: Garnett, James P., Hickman, Emma, Burrows, Rachel, Hegyi, Péter, Tiszlavicz, László, Cuthbert, Alan W., Fong, Peying, Gray, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220502/
https://ncbi.nlm.nih.gov/pubmed/21914796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266734
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