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Most bicarbonate secretion by Calu‐3 cells is mediated by CFTR and independent of pendrin

Bicarbonate plays an important role in airway host defense, however, its transport mechanisms remain uncertain. Here we examined the relative contributions of the anion channel CFTR (cystic fibrosis transmembrane conductance regulator, ABCC7) and the anion exchanger pendrin (SLC26A4) to HCO (3) (−)...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Huang, Junwei, Kim, Dusik, Shan, Jiajie, Abu‐Arish, Asmahan, Luo, Yishan, Hanrahan, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849580/
https://ncbi.nlm.nih.gov/pubmed/29536650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13641
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