Bicarbonate-dependent chloride transport drives fluid secretion by the human airway epithelial cell line Calu-3

Anion and fluid secretion are both defective in cystic fibrosis (CF); however, the transport mechanisms are not well understood. In this study, Cl(−) and HCO(3)(−) secretion was measured using genetically matched CF transmembrane conductance regulator (CFTR)-deficient and CFTR-expressing cell lines...

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Main Authors: Shan, Jiajie, Liao, Jie, Huang, Junwei, Robert, Renaud, Palmer, Melissa L, Fahrenkrug, Scott C, O'Grady, Scott M, Hanrahan, John W
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2012
Ábhair:
Molecular and Cellular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515819/
https://ncbi.nlm.nih.gov/pubmed/22777674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.236893
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