Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules

HopQ is an outer-membrane protein of Helicobacter pylori that binds to human carcinoembryonic antigen-related cell-adhesion molecules (CEACAMs) with high specificity. We aimed to investigate fluorescence targeting of CEACAM-expressing colorectal tumors in patient-derived orthotopic xenograft (PDOX)...

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Detalhes bibliográficos
Publicado no:Transl Oncol
Main Authors: Hollandsworth, Hannah M., Schmitt, Verena, Amirfakhri, Siamak, Filemoni, Filemoni, Schmidt, Alexej, Landström, Maréne, Lyndin, Mykola, Backert, Steffen, Gerhard, Markus, Wennemuth, Gunther, Hoffman, Robert M., Singer, Bernhard B., Bouvet, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475271/
https://ncbi.nlm.nih.gov/pubmed/32866936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100857
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