Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models

Background: Monoclonal antibody (mAb) 6G5j is a novel anti-CEACAM monoclonal antibody. Our aim was to investigate mAb 6G5j binding characteristics and to validate fluorescence targeting of colorectal tumors and metastases in patient derived orthotopic xenograft (PDOX) models with fluorescently label...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hollandsworth, Hannah M., Amirfakhri, Siamak, Filemoni, Filemoni, Schmitt, Verena, Wennemuth, Gunther, Schmidt, Alexej, Hoffman, Robert M., Singer, Bernhard B., Bouvet, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996915/
https://ncbi.nlm.nih.gov/pubmed/32064046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27446
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