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Role of the C9ORF72 Gene in the Pathogenesis of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Since the discovery of the C9ORF72 gene in 2011, great advances have been achieved in its genetics and in identifying its role in disease models and pathological mechanisms; it is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). ALS patients wit...

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Détails bibliographiques
Publié dans:Neurosci Bull
Auteurs principaux: Hao, Zongbing, Wang, Rui, Ren, Haigang, Wang, Guanghui
Format: Artigo
Langue:Inglês
Publié: Springer Singapore 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475143/
https://ncbi.nlm.nih.gov/pubmed/32860626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00567-7
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