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C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia: gain or loss of function?
PURPOSE OF REVIEW: The molecular mechanisms that underlie chromosome 9 open reading frame 72 (C9orf72)-associated amyotrophic lateral sclerosis and frontotemporal dementia are rapidly emerging. Two potential disease mechanisms have been postulated – gain or loss of function. We provide an overview o...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4165481/ https://ncbi.nlm.nih.gov/pubmed/25188012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0000000000000130 |
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