Molecular, clinicopathological, and immune correlates of LAG3 promoter DNA methylation in melanoma

BACKGROUND: The co-receptor lymphocyte-activation gene-3 (LAG3, LAG-3, CD223) is a potential target for immune checkpoint inhibition immunotherapies. However, little is known about the biological and clinical significance of LAG3 DNA methylation in melanoma and its microenvironment. METHODS: We eval...

詳細記述

保存先:
書誌詳細
出版年:EBioMedicine
主要な著者: Fröhlich, Anne, Sirokay, Judith, Fietz, Simon, Vogt, Timo J., Dietrich, Jörn, Zarbl, Romina, Florin, Mike, Kuster, Pia, Saavedra, Gonzalo, Valladolid, Susana Ramírez, Hoffmann, Friederike, Flatz, Lukas, Ring, Sandra S., Golletz, Carsten, Pietsch, Torsten, Strieth, Sebastian, Brossart, Peter, Gielen, Gerrit H., Kristiansen, Glen, Bootz, Friedrich, Landsberg, Jennifer, Dietrich, Dimo
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2020
主題:
Research paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7475111/
https://ncbi.nlm.nih.gov/pubmed/32861198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.102962
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