Prognostic and predictive value of PD-L2 DNA methylation and mRNA expression in melanoma

BACKGROUND: PD-L1 (programmed cell death 1 ligand 1) expression in melanoma has been associated with a better response to anti-PD-1 (programmed cell death 1) therapy. However, patients with PD-L1-negative melanomas can respond to anti-PD-1 blockade, suggesting that the other PD-1 ligand, PD-L2 (prog...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Hoffmann, Friederike, Zarbl, Romina, Niebel, Dennis, Sirokay, Judith, Fröhlich, Anne, Posch, Christian, Holderried, Tobias A. W., Brossart, Peter, Saavedra, Gonzalo, Kuster, Pia, Strieth, Sebastian, Gielen, Gerrit H., Ring, Sandra S., Dietrich, Jörn, Pietsch, Torsten, Flatz, Lukas, Kristiansen, Glen, Landsberg, Jennifer, Dietrich, Dimo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318478/
https://ncbi.nlm.nih.gov/pubmed/32586358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00883-9
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