Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion

Syntaxin17, a key autophagosomal N-ethylmaleimide–sensitive factor attachment protein receptor (SNARE) protein, can associate with ATG8 family proteins SNAP29 and VAMP8 to facilitate the membrane fusion process between the double-membraned autophagosome and single-membraned lysosome in mammalian mac...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Li, Ying, Cheng, Xiaofang, Li, Miao, Wang, Yingli, Fu, Tao, Zhou, Zixuan, Wang, Yaru, Gong, Xinyu, Xu, Xiaolong, Liu, Jianping, Pan, Lifeng
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474698/
https://ncbi.nlm.nih.gov/pubmed/32817423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006997117
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