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Talin folding as the tuning fork of cellular mechanotransduction

Cells continually sample their mechanical environment using exquisite force sensors such as talin, whose folding status triggers mechanotransduction pathways by recruiting binding partners. Mechanical signals in biology change quickly over time and are often embedded in noise; however, the mechanics...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tapia-Rojo, Rafael, Alonso-Caballero, Álvaro, Fernández, Julio M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474635/
https://ncbi.nlm.nih.gov/pubmed/32817549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004091117
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