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Talin folding as the tuning fork of cellular mechanotransduction

Cells continually sample their mechanical environment using exquisite force sensors such as talin, whose folding status triggers mechanotransduction pathways by recruiting binding partners. Mechanical signals in biology change quickly over time and are often embedded in noise; however, the mechanics...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Tapia-Rojo, Rafael, Alonso-Caballero, Álvaro, Fernández, Julio M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474635/
https://ncbi.nlm.nih.gov/pubmed/32817549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004091117
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