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Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins
Bacteria anchor to their host cells through their adhesive pili, which must resist the large mechanical stresses induced by the host as it attempts to dislodge the pathogens. The pili of gram-positive bacteria are constructed as a single polypeptide made of hundreds of pilin repeats, which contain i...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140542/ https://ncbi.nlm.nih.gov/pubmed/30150415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807689115 |
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