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Molecular strategy for blocking isopeptide bond formation in nascent pilin proteins

Bacteria anchor to their host cells through their adhesive pili, which must resist the large mechanical stresses induced by the host as it attempts to dislodge the pathogens. The pili of gram-positive bacteria are constructed as a single polypeptide made of hundreds of pilin repeats, which contain i...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Rivas-Pardo, Jaime Andrés, Badilla, Carmen L., Tapia-Rojo, Rafael, Alonso-Caballero, Álvaro, Fernández, Julio M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6140542/
https://ncbi.nlm.nih.gov/pubmed/30150415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807689115
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