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DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses
The sulfur atom of phosphorothioated DNA (PT-DNA) is coordinated by a surface cavity in the conserved sulfur-binding domain (SBD) of type IV restriction enzymes. However, some SBDs cannot recognize the sulfur atom in some sequence contexts. To illustrate the structural determinants for sequence spec...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470945/ https://ncbi.nlm.nih.gov/pubmed/32621606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa574 |
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