DNA backbone interactions impact the sequence specificity of DNA sulfur-binding domains: revelations from structural analyses

The sulfur atom of phosphorothioated DNA (PT-DNA) is coordinated by a surface cavity in the conserved sulfur-binding domain (SBD) of type IV restriction enzymes. However, some SBDs cannot recognize the sulfur atom in some sequence contexts. To illustrate the structural determinants for sequence spec...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Yu, Hao, Li, Jiayi, Liu, Guang, Zhao, Gong, Wang, Yuli, Hu, Wenyue, Deng, Zixin, Wu, Geng, Gan, Jianhua, Zhao, Yi-Lei, He, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470945/
https://ncbi.nlm.nih.gov/pubmed/32621606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa574
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados