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Structural basis for the recognition of sulfur in phosphorothioated DNA

There have been very few reports on protein domains that specifically recognize sulfur. Here we present the crystal structure of the sulfur-binding domain (SBD) from the DNA phosphorothioation (PT)-dependent restriction endonuclease ScoMcrA. SBD contains a hydrophobic surface cavity that is formed b...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Liu, Guang, Fu, Wencheng, Zhang, Zhenyi, He, Yao, Yu, Hao, Wang, Yuli, Wang, Xiaolei, Zhao, Yi-Lei, Deng, Zixin, Wu, Geng, He, Xinyi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224610/
https://ncbi.nlm.nih.gov/pubmed/30409991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07093-1
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