Cleavage of Phosphorothioated DNA and Methylated DNA by the Type IV Restriction Endonuclease ScoMcrA

Many taxonomically diverse prokaryotes enzymatically modify their DNA by replacing a non-bridging oxygen with a sulfur atom at specific sequences. The biological implications of this DNA S-modification (phosphorothioation) were unknown. We observed that simultaneous expression of the dndA-E gene clu...

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Detalhes bibliográficos
Main Authors: Liu, Guang, Ou, Hong-Yu, Wang, Tao, Li, Li, Tan, Huarong, Zhou, Xiufen, Rajakumar, Kumar, Deng, Zixin, He, Xinyi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009677/
https://ncbi.nlm.nih.gov/pubmed/21203499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001253
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