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Enzymatic Cleavage of Type II Restriction Endonucleases on the 2′-O-Methyl Nucleotide and Phosphorothioate Substituted DNA

The effects of nucleotide analogue substitution on the cleavage efficiencies of type II restriction endonucleases have been investigated. Six restriction endonucleases (EcoRV, SpeI, XbaI, XhoI, PstI and SphI) were investigated respectively regarding their cleavage when substrates were substituted by...

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Autori principali: Zhao, Guojie, Li, Jun, Tong, Zhaoxue, Zhao, Bin, Mu, Runqing, Guan, Yifu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829850/
https://ncbi.nlm.nih.gov/pubmed/24260216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079415
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