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Structural basis for the recognition of sulfur in phosphorothioated DNA

There have been very few reports on protein domains that specifically recognize sulfur. Here we present the crystal structure of the sulfur-binding domain (SBD) from the DNA phosphorothioation (PT)-dependent restriction endonuclease ScoMcrA. SBD contains a hydrophobic surface cavity that is formed b...

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Publicado en:Nat Commun
Autores principales: Liu, Guang, Fu, Wencheng, Zhang, Zhenyi, He, Yao, Yu, Hao, Wang, Yuli, Wang, Xiaolei, Zhao, Yi-Lei, Deng, Zixin, Wu, Geng, He, Xinyi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224610/
https://ncbi.nlm.nih.gov/pubmed/30409991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07093-1
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