The Chemokine-like Receptor 1 Deficiency Improves Cognitive Deficits of AD Mice and Attenuates Tau Hyperphosphorylation via Regulating Tau Seeding

Pathologic features of Alzheimer's disease (AD) include accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein. We have shown previously that the chemokine-like receptor 1 (CMKLR1) is a functional receptor for Aβ, and CMKLR1 contributes to the uptake of Aβ. However, it is unclear wh...

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Detalhes bibliográficos
Publicado no:J Neurosci
Principais autores: Zhang, Haibo, Lin, Aihua, Gong, Ping, Chen, Yanqing, Ye, Richard D., Qian, Feng, Zhang, Yan, Yu, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470913/
https://ncbi.nlm.nih.gov/pubmed/32801154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0455-20.2020
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