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p47(phox) deficiency improves cognitive impairment and attenuates tau hyperphosphorylation in mouse models of AD
BACKGROUND: Alzheimer’s disease (AD) is characterized by progressive memory loss and cognitive impairment. The aggregation of amyloid β (Aβ) and hyperphosphorylated tau protein are two major pathological features of AD. Nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase, NOX) has bee...
Gorde:
| Argitaratua izan da: | Alzheimers Res Ther |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
BioMed Central
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7659091/ https://ncbi.nlm.nih.gov/pubmed/33183342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-020-00714-2 |
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