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Preclinical PK/PD model for the combinatorial use of dexamethasone and sulpiride in the treatment of breast cancer
Previous studies show that dopamine D(2)-like receptor (D2DR) antagonist sulpiride (SUL) enhances the antitumor efficacy of dexamethasone (DEX) in drug-resistant breast cancer involving cancer stem-like cells (CSCs). In this study, we investigated the pharmacokinetic (PK) properties of SUL in nude m...
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| 出版年: | Acta Pharmacol Sin |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470835/ https://ncbi.nlm.nih.gov/pubmed/31165782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0251-7 |
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