Dopamine D2 receptor antagonist sulpiride enhances dexamethasone responses in the treatment of drug-resistant and metastatic breast cancer

Recent evidence shows that dopamine D2-like receptor (D2DR) antagonists, such as trifluoperazine and thioridazine, are effective for cancer therapy and inhibition of cancer stem-like cells (CSCs). In this study, we investigated the anti-cancer effects of combination therapy of dexamethasone (DEX) an...

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Publicat a:Acta Pharmacol Sin
Autors principals: Li, Jian, Yao, Qing-yu, Xue, Jun-sheng, Wang, Li-jie, Yuan, Yin, Tian, Xiu-yun, Su, Hong, Wang, Si-yuan, Chen, Wen-jun, Lu, Wei, Zhou, Tian-yan
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589964/
https://ncbi.nlm.nih.gov/pubmed/28649130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2017.24
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