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Upregulation of TRPM3 in nociceptors innervating inflamed tissue
Genetic ablation or pharmacological inhibition of the heat-activated cation channel TRPM3 alleviates inflammatory heat hyperalgesia, but the underlying mechanisms are unknown. We induced unilateral inflammation of the hind paw in mice, and directly compared expression and function of TRPM3 and two o...
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| Publié dans: | eLife |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications, Ltd
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7470828/ https://ncbi.nlm.nih.gov/pubmed/32880575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61103 |
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