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Upregulation of TRPM3 in nociceptors innervating inflamed tissue

Genetic ablation or pharmacological inhibition of the heat-activated cation channel TRPM3 alleviates inflammatory heat hyperalgesia, but the underlying mechanisms are unknown. We induced unilateral inflammation of the hind paw in mice, and directly compared expression and function of TRPM3 and two o...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Mulier, Marie, Van Ranst, Nele, Corthout, Nikky, Munck, Sebastian, Vanden Berghe, Pieter, Vriens, Joris, Voets, Thomas, Moilanen, Lauri
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470828/
https://ncbi.nlm.nih.gov/pubmed/32880575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61103
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