Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models

Limb-girdle muscular dystrophy type 2B (LGMD2B) is caused by mutations in the dysferlin gene, resulting in non-functional dysferlin, a key protein found in muscle membrane. Treatment options available for patients are chiefly palliative in nature and focus on maintaining ambulation. Our hypothesis i...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vallecillo-Zúniga, Mary L., Rathgeber, Matthew F., Poulson, P. Daniel, Hayes, Spencer, Luddington, Jacob S., Gill, Hailie N., Teynor, Matthew, Kartchner, Braden C., Valdoz, Jonard, Stowell, Caleb, Markham, Ashley R., Arthur, Connie, Stowell, Sean, Van Ry, Pam M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470338/
https://ncbi.nlm.nih.gov/pubmed/32881965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238441
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