Treatment with galectin-1 improves myogenic potential and membrane repair in dysferlin-deficient models

Limb-girdle muscular dystrophy type 2B (LGMD2B) is caused by mutations in the dysferlin gene, resulting in non-functional dysferlin, a key protein found in muscle membrane. Treatment options available for patients are chiefly palliative in nature and focus on maintaining ambulation. Our hypothesis i...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Vallecillo-Zúniga, Mary L., Rathgeber, Matthew F., Poulson, P. Daniel, Hayes, Spencer, Luddington, Jacob S., Gill, Hailie N., Teynor, Matthew, Kartchner, Braden C., Valdoz, Jonard, Stowell, Caleb, Markham, Ashley R., Arthur, Connie, Stowell, Sean, Van Ry, Pam M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470338/
https://ncbi.nlm.nih.gov/pubmed/32881965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238441
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