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GREG cells, a dysferlin-deficient myogenic mouse cell line

The dysferlinopathies (e.g. LGMD2b, Myoshi myopathy) are progressive, adult-onset muscle wasting syndromes caused by mutations in the gene coding for dysferlin. Dysferlin is a large (~200 kDa) membrane-anchored protein, required for maintenance of plasmalemmal integrity in muscle fibers. To facilita...

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Bibliographic Details
Main Authors: Humphrey, Glen W., Mekhedov, Elena, Blank, Paul S., de Morree, Antoine, Pekkurnaz, Gulcin, Nagaraju, Kanneboyina, Zimmerberg, Joshua
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3541016/
https://ncbi.nlm.nih.gov/pubmed/22020321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.10.004
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