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Dexamethasone induces dysferlin in myoblasts and enhances their myogenic differentiation

Glucocorticoids are beneficial in many muscular dystrophies but they are ineffective in treating dysferlinopathy, a rare muscular dystrophy caused by loss of dysferlin. We sought to understand the molecular basis for this disparity by studying the effects of a glucocorticoid on differentiation of th...

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Main Authors: Belanto, Joseph J., Diaz-Perez, Silvia V., Magyar, Clara E., Maxwell, Michele M., Yilmaz, Yasemin, Topp, Kasey, Boso, Guney, Jamieson, Catriona H., Cacalano, Nicholas A., Jamieson, Christina A.M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856642/
https://ncbi.nlm.nih.gov/pubmed/20080405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2009.12.003
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