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Fluorescent labeled antibodies - balancing functionality and degree of labeling

A critical assumption in utilizing labeled antibodies is that the conjugation reaction has no deleterious effects on antibody avidity. This study demonstrates that this assumption need not hold true and presents a methodology to quantitatively determine the degree of inactivation and/or changes in a...

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Detalhes bibliográficos
Main Authors: Vira, Shaleen, Mekhedov, Elena, Humphrey, Glen, Blank, Paul S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876214/
https://ncbi.nlm.nih.gov/pubmed/20362543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.03.036
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