Inflammasome Up-Regulation and Activation in Dysferlin-Deficient Skeletal Muscle

A deficiency of the dysferlin protein results in limb girdle muscular dystrophy type 2B and Miyoshi myopathy, with resulting plasma membrane abnormalities in myofibers. Many patients show muscle inflammation, but the molecular mechanisms that initiate and perpetuate this inflammation are not well un...

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Detalhes bibliográficos
Main Authors: Rawat, Rashmi, Cohen, Tatiana V., Ampong, Beryl, Francia, Dwight, Henriques-Pons, Andrea, Hoffman, Eric P., Nagaraju, Kanneboyina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877850/
https://ncbi.nlm.nih.gov/pubmed/20413686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090058
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