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Inflammasome Up-Regulation and Activation in Dysferlin-Deficient Skeletal Muscle
A deficiency of the dysferlin protein results in limb girdle muscular dystrophy type 2B and Miyoshi myopathy, with resulting plasma membrane abnormalities in myofibers. Many patients show muscle inflammation, but the molecular mechanisms that initiate and perpetuate this inflammation are not well un...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Investigative Pathology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877850/ https://ncbi.nlm.nih.gov/pubmed/20413686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090058 |
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