Inflammasome Up-Regulation and Activation in Dysferlin-Deficient Skeletal Muscle

A deficiency of the dysferlin protein results in limb girdle muscular dystrophy type 2B and Miyoshi myopathy, with resulting plasma membrane abnormalities in myofibers. Many patients show muscle inflammation, but the molecular mechanisms that initiate and perpetuate this inflammation are not well un...

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Autori principali: Rawat, Rashmi, Cohen, Tatiana V., Ampong, Beryl, Francia, Dwight, Henriques-Pons, Andrea, Hoffman, Eric P., Nagaraju, Kanneboyina
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2010
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877850/
https://ncbi.nlm.nih.gov/pubmed/20413686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090058
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