Dysferlin Deficiency Enhances Monocyte Phagocytosis: A Model for the Inflammatory Onset of Limb-Girdle Muscular Dystrophy 2B

Dysferlin deficiency causes limb-girdle muscular dystrophy type 2B (LGMD2B; proximal weakness) and Miyoshi myopathy (distal weakness). Muscle inflammation is often present in dysferlin deficiency, and patients are frequently misdiagnosed as having polymyositis. Because monocytes normally express dys...

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Detalhes bibliográficos
Main Authors: Nagaraju, Kanneboyina, Rawat, Rashmi, Veszelovszky, Edina, Thapliyal, Rachana, Kesari, Akanchha, Sparks, Susan, Raben, Nina, Plotz, Paul, Hoffman, Eric P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258254/
https://ncbi.nlm.nih.gov/pubmed/18276788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070327
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