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ATAD5 suppresses centrosome over-duplication by regulating UAF1 and ID1

Centrosomes are the primary microtubule-organizing centers that are important for mitotic spindle assembly. Centrosome amplification is commonly observed in human cancer cells and contributes to genomic instability. However, it is not clear how centrosome duplication is dysregulated in cancer cells....

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Bibliografiske detaljer
Udgivet i:Cell Cycle
Main Authors: Kim, Seong-jung, Wie, Minwoo, Park, Su Hyung, Kim, Tae Moon, Park, Jun Hong, Kim, Shinseog, Myung, Kyungjae, Lee, Kyoo-young
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469630/
https://ncbi.nlm.nih.gov/pubmed/32594826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1785724
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