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Dysregulation of TFEB contributes to manganese-induced autophagic failure and mitochondrial dysfunction in astrocytes

Epidemiological and clinical studies have long shown that exposure to high levels of heavy metals are associated with increased risks of neurodegenerative diseases. It is widely accepted that autophagic dysfunction is involved in pathogenesis of various neurodegenerative disorders; however, the role...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Ziyan, Yan, Jingqi, Bowman, Aaron B., Bryan, Miles R., Singh, Rajat, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469609/
https://ncbi.nlm.nih.gov/pubmed/31690173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1688488
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