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Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures

Chronic exposure to excessive levels of Mn results in a movement disorder termed manganism, which resembles Parkinson’s disease (PD). The pathogenic mechanisms underlying this disorder are not fully understood. Several lines of evidence implicate astrocytes as an early target of Mn neurotoxicity. In...

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Detalhes bibliográficos
Main Authors: Yin, Zhaoobao, Aschner, Judy L., Santos, Ana Paula dos, Aschner, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327216/
https://ncbi.nlm.nih.gov/pubmed/18313649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.01.079
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