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Mitochondrial-dependent manganese neurotoxicity in rat primary astrocyte cultures

Chronic exposure to excessive levels of Mn results in a movement disorder termed manganism, which resembles Parkinson’s disease (PD). The pathogenic mechanisms underlying this disorder are not fully understood. Several lines of evidence implicate astrocytes as an early target of Mn neurotoxicity. In...

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Autori principali: Yin, Zhaoobao, Aschner, Judy L., Santos, Ana Paula dos, Aschner, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2327216/
https://ncbi.nlm.nih.gov/pubmed/18313649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2008.01.079
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