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Manganese-induced Mitochondrial Dysfunction Is Not Detectable at Exposures Below the Acute Cytotoxic Threshold in Neuronal Cell Types

Manganese (Mn) is an essential metal, but excessive exposures have been well-documented to culminate in neurotoxicity. Curiously, the precise mechanisms of Mn neurotoxicity are still unknown. One hypothesis suggests that Mn exerts its toxicity by inhibiting mitochondrial function, which then (if exp...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Toxicol Sci
Main Authors: Warren, Emily B, Bryan, Miles R, Morcillo, Patricia, Hardeman, Keisha N, Aschner, Michael, Bowman, Aaron B
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416316/
https://ncbi.nlm.nih.gov/pubmed/32492146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa079
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