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Tuft cell-derived leukotrienes drive rapid anti-helminth immunity in the small intestine but are dispensable for anti-protist immunity
Helminths, allergens, and certain protists induce type 2 immune responses, but the underlying mechanisms of immune activation remain poorly understood. In the small intestine, chemosensing by epithelial tuft cells results in activation of group 2 innate lymphoid cells (ILC2s), which subsequently dri...
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| Gepubliceerd in: | Immunity |
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| Hoofdauteurs: | , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7469474/ https://ncbi.nlm.nih.gov/pubmed/32160525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.02.005 |
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