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Tuft cell-derived leukotrienes drive rapid anti-helminth immunity in the small intestine but are dispensable for anti-protist immunity

Helminths, allergens, and certain protists induce type 2 immune responses, but the underlying mechanisms of immune activation remain poorly understood. In the small intestine, chemosensing by epithelial tuft cells results in activation of group 2 innate lymphoid cells (ILC2s), which subsequently dri...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: McGinty, John W., Ting, Hung-An, Billipp, Tyler E., Nadjsombati, Marija S., Khan, Danish M., Barrett, Nora A., Liang, Hong-Erh, Matsumoto, Ichiro, von Moltke, Jakob
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469474/
https://ncbi.nlm.nih.gov/pubmed/32160525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.02.005
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