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Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit
Parasitic helminths and allergens induce a type 2 immune response leading to profound changes in tissue physiology, including hyperplasia of mucus-secreting goblet cells(1) and smooth muscle hypercontractility(2). This response, known as ‘weep and sweep’, requires interleukin (IL)-13 production by t...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4830391/ https://ncbi.nlm.nih.gov/pubmed/26675736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16161 |
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