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WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice

The global prevalence of nonalcoholic steatohepatitis (NASH) increases incredibly. NASH ends up to advanced liver disease, which is highly threatening to human health. Currently, treatment of NASH is very limited. Acetyl-CoA carboxylases (ACC1/ACC2) are proved as effective drug targets for NASH. We...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Gao, Ying-sheng, Qian, Min-yi, Wei, Qiang-qiang, Duan, Xu-bin, Wang, Shi-lei, Hu, Hai-yang, Liu, Jun, Pan, Chu-yue, Zhang, Shuo-quan, Qi, Lian-wen, Zhou, Jin-pei, Zhang, Hui-bin, Wang, Li-rui
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468331/
https://ncbi.nlm.nih.gov/pubmed/31645659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0310-0
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