WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice

The global prevalence of nonalcoholic steatohepatitis (NASH) increases incredibly. NASH ends up to advanced liver disease, which is highly threatening to human health. Currently, treatment of NASH is very limited. Acetyl-CoA carboxylases (ACC1/ACC2) are proved as effective drug targets for NASH. We...

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Xehetasun bibliografikoak
Argitaratua izan da:Acta Pharmacol Sin
Egile Nagusiak: Gao, Ying-sheng, Qian, Min-yi, Wei, Qiang-qiang, Duan, Xu-bin, Wang, Shi-lei, Hu, Hai-yang, Liu, Jun, Pan, Chu-yue, Zhang, Shuo-quan, Qi, Lian-wen, Zhou, Jin-pei, Zhang, Hui-bin, Wang, Li-rui
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Singapore 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468331/
https://ncbi.nlm.nih.gov/pubmed/31645659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-019-0310-0
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