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Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae
Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inversions combined with whole-genome sequencing to st...
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| Pubblicato in: | eLife |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
eLife Sciences Publications, Ltd
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467729/ https://ncbi.nlm.nih.gov/pubmed/32762846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58223 |
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