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Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae

Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a Saccharomyces cerevisiae genetic system that generates gross chromosomal rearrangements (GCRs) mediated by foldback inversions combined with whole-genome sequencing to st...

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Bibliografische gegevens
Gepubliceerd in:eLife
Hoofdauteurs: Li, Bin-zhong, Putnam, Christopher D, Kolodner, Richard David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: eLife Sciences Publications, Ltd 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7467729/
https://ncbi.nlm.nih.gov/pubmed/32762846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.58223
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