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Saccharomyces cerevisiae as a Model System To Define the Chromosomal Instability Phenotype

Translocations, deletions, and chromosome fusions are frequent events seen in cancers with genome instability. Here we analyzed 358 genome rearrangements generated in Saccharomyces cerevisiae selected by the loss of the nonessential terminal segment of chromosome V. The rearrangements appeared to be...

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Main Authors: Putnam, Christopher D., Pennaneach, Vincent, Kolodner, Richard D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1190249/
https://ncbi.nlm.nih.gov/pubmed/16055731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.16.7226-7238.2005
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